Dr. Diamond’s Metacine line has a heavy focus on the Plasma Serum, alongside the Emulsion and Infusion.

Overall sentiment is highly polarized: some users describe visible, even dramatic improvements—especially around the eyes—while others see minimal or no change despite long-term use. The extreme price point is the single biggest point of friction.

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The Good

• Visible Skin Improvements: Some users report fast, noticeable changes in texture, tone, and pigmentation: “Instant difference… pores less, texture smoother, even color.” (2 upvotes)
• The eye area is where the product appears to perform best: “Huge reduction in lines and crow’s feet.” (1 upvote)
  “Biggest difference after 2 months was wrinkles around my eyes.” (2 upvotes)
• Long-Term Satisfaction (for Some): “Using the combo nearly every day… game changer.” (18 upvotes)
• Glow & Suppleness: Several users describe improved radiance rather than dramatic correction.: “It imparts a beautiful glow and makes skin more supple.” (1 upvote)
  

The Not So Good

• No Visible Results: extended use without meaningful improvement. “Used every day for 8 months and noticed absolutely no changes.” (2 upvotes)
  “After one year… not great for the price.” (1 upvote)
• Diminishing Returns: Some users see early results that plateau: “Hit a plateau—stopped seeing benefit.” (5 upvotes)
• Price vs Performance: Even satisfied users question the value: “Not worth the squeeze.” (9 upvotes) “At $800, it doesn’t feel like $800 skin.” (2 upvotes)
• Eye sensitivity“Makes my eyes burn… even when not applying near them.” (2 upvotes)
• Breakouts (post-treatment)“Skin looks great the day after… then I break out.” (1 upvote) “Woke up with redness on cheeks and nose.” (3 upvotes)

How It Compares

• Versus NeoGenesis Recovery: “I like Recovery better.” (7 upvotes)
  
• Versus Traditional Actives: Some users argue the price isn’t justified vs proven ingredients: “Beyond retinoids, vitamin C, sunscreen… other topicals won’t make a big difference.” (13 upvotes)
  
• Versus Other Luxury Serums
  • Dior Micro Huile de Rose: Metacine preferred by some (2 upvotes)
  • Eighth Day Regenerative Serum: Frequently recommended alternative (2 upvotes)
  • TNS Advanced: Mixed to disappointing results (2 upvotes)

Community Tips

• Use less than you think (4 drops is enough)
• Target use (eyes or mouth area only to extend lifespan)
• Unscrew packaging to access leftover product
• Avoid layering with other retinoids if using the Emulsion

Final Verdict

Reddit sentiment on Dr. Diamond Metacine Plasma Serum is sharply divided.

Pros

• Visible improvement for some users, especially around the eyes
• Noticeable glow and smoother texture
• Works well for a subset of skin types

Cons

• Extremely expensive
• Results are inconsistent
• Can cause irritation, dryness, or plateauing
• Often compared unfavorably to both cheaper actives and competing growth-factor serums

Bottom line:
For some users, Metacine delivers meaningful results—but the risk is high. Most Redditors recommend waiting for deep discounts, trying targeted application first, or opting for more established alternatives with a better price-to-performance ratio.

This is a high-reward, high-regret product depending entirely on how your skin responds.

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